We provide quality products and services, consistently,
reliably responsibly and continuously applying some of the world’s
most difficult to handle chemical technologies.
Our independent one-site,
single entity corporate setup enables
Easiness to deal
Focus on customers
History Lodi Site
Foundation of Istituto Chemioterapico Italiano (I.C.I.)
Foundation of Prime European Therapeuticals S.p.A (Euticals)
Mandarin Capital Partners becomes majority Euticals shareholder
Clessidra, an Italian Financial Fund becomes majority Euticals shareholder
AMRI acquired Euticals Group
Effective August 1, Livia acquires Lodi site, and brands it Archimica S.p.A.
Own products (APIs) for the generic pharmaceutical industry.
Synthesis: Manufacturing services and products for all user industries,
using Archimica´s highly differentiated setup and technologies
APIs, Building blocks, GMP intermediates
For all global markets including the United States of America,
in total Archimica products reach 25 countries.
API - Active Pharmaceutical Ingredient Products
- Glycerophosphoryl-Choline (GPC)
- Glycerophosphorylethanolamine (GPE)
- Mianserin Hydrochloride
- Pyridine/Sulfur Trioxide
- Sucrose Octasulfate Sodium/Potassium salt
- Amtolmetin Guacil
- Aurothiomalate Sodium
- Dihydralazine sulfate
- Hydralazine hydrochloride
- Lithium Carbonate
- Pirenzepine Dihydrochloride
Technologies & Plant
BUSINESS & ADMINISTRATION
Reactor Capacity: About 250 m3 (stainless steel and glass line).
Temperature Range: -20 to 150°.
Pressure Range: 10 mbar to 5 bar.
Reactor/Vessel Volume Range: 50 to 10.000 liter.
Dryers: Fluid bed dryer, agitated vacuum pan dryer, vacuum horizontal agitated dryer, vacuum double cone dryer, Planex® dryer, tray dryer.
Centrifuges: Vertical axis top discharge centrifuges, vertical axis bottom discharge centrifuges, horizontal axis peeler centrifuges.
Ancillary Equipment: Filter Press, Sieves, Filters, Ultra Filters.
F1 – QC Laboratory
F2A – Multi-Purpose Plant
F3A – Raw Materials, Intermediates and APIs warehouse
F3B – Finishing & Drying Plant (ISO 8, controlled environment)
F5A – Hydroxyurea Plant
F5B – Multi-Purpose Plant
F5C – Cytarabine Plant
F6A – Sucralfate Plant
F6B – Sulfamidics Plant
F7 – Multi-Purpose Plant
F8 – Utilities
Highly flexible and broad permit for all technologies, reagents and solvents.
Broad range of extraordinary hazardous chemistry and chemicals processable in large scale:
solvents, including chlorinated and toxic solvents;
Strong acids including phosphorous oxychloride, chlorosulfonicacid, hydrofluoric acid;
Highly flammable, highly corrosive, explosive chemicals.
Residual thermal oxidizer allowing trace gas contamination removal, all waste gas streams.
Seveso guideline compliant.
Own on-site waste water treatment, backed by external partners.
Solvent recovery and tank farms.
Large Scale Deacylated Phospholipids production (GPC, GPE)
Large Scale Use of Pyridine as reagent or solvent, as well as pyridine-SO3 complex handling.
Cytostatics manufacturing/drying: Nucleosides.
Heterocyclic chemistry: Pyridines, Piperazines, Quinoxalines, Quinolones, Quinazolinones, Benzofuranes.
Chromatographic purification with ionic resins.
Micronization (third party partners).
Hydrazine, Azides, Diphenyl-phosphorylazide, Acetyl Nitrate
Fluorine, chlorine, bromine, iodine
Chlorine, chlorinating agents
Bromine, brominating agents (NBS, dibromohydantoin, phosphorous bromides)
Methylene diiodide, methyliodide, iodoform, TMSOZ